Home - Products - Microbiology/Virology - Parasite - Antitrypanosomal agent 1

Antitrypanosomal agent 1

CAS No. 75144-12-6

Antitrypanosomal agent 1( —— )

Catalog No. M26057 CAS No. 75144-12-6

Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM).

Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
100MG	68	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Antitrypanosomal agent 1
Note

Research use only, not for human use.
Brief Description

Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM).
Description

Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
In Vitro

Antitrypanosomal agent 1 (compound 8a) has an selectivity for TR (GR IC50/TR IC50) of 20.
In Vivo

——
Synonyms

——
Pathway

Microbiology/Virology
Target

Parasite
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

75144-12-6
Formula Weight

282.59
Molecular Formula

C11H14Cl3NO
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 25 mg/mL (88.47 mM)
SMILES

Cl.CN(C)CCC(=O)c1ccc(Cl)c(Cl)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Aranya Manosroi, et al. Melanogenesis of methyl myristate loaded niosomes in B16F10 melanoma cells. J Biomed Nanotechnol. 2013 Apr;9(4):626-38.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

N-(2-Hydroxypropyl)m...

N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.
Picaridin

Picaridin is a topical insect repellent.
Spirodiclofen

Spirodiclofen is a selective, non-systemic acaricide from the new chemical class of tetronic acid derivatives,with no cross resistance to currently available acaricides and with additional insecticidal properties.

Sign In Join Free